General Cell Lines and Cell Cultures
Eurofins Discoverx cAMP Hunter CHO-K1 SSTR4 Gi Cell Line, 2 vials. (95-0059C2)
The cAMP Hunter SSTR4 Gi cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. somatostatin 28) based activation of SSTR4 GPCR activity via detection of decreasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type SSTR4, a naturally Gi/Go coupled GPCR. Upon activation of SSTR4, the decrease in levels of intracellular cAMP leads to a decreased signal from EFC when the cAMP detection kit is applied. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
ATCC NIT-1; Insulinoma; Mouse (Mus musculus)
NIT-1 is a beta cell line that was isolated from the islet of Langerhans of a 10-week-old, female mouse with insulinoma. This cell line was deposited by EH Leiter.
ATCC CCD-1064Sk; Fibroblast; Human (Homo sapiens)
CCD-1064Sk is a cell line exhibiting fibroblast morphology that was isolated from the skin of a male patient.
Lonza Walkersville Rat Brain Hypothalamus Neurons
The hypothalamus is responsible for many metabolic processes and other activities of the autonomic nervous system. It synthesizes and secretes neurohormones, that stimulate or inhibit the secretion of pituitary hormones. The hypothalamus controls body temperature, hunger, thirst, fatigue, and circadian cycles. Rat hypothalamus neurons are a useful tool in the study of neuroendocrine-related diseases and disorders.Benefits:Ready-To-Use No tissue dissection or animal handling required Increased data reproducibilityCharacteristic morphology and staining tests confirm tissue origin and cell typeNegative for mycoplasma, bacteria, yeast and fungiCertificate of Analysis (CoA) is available for every batchApplications:NeurogenesisNeurotransmitter FunctionGene ExpressionSignaling PathwaysElectrophysiologyNeurotoxicityDrug/Compound ScreeningAdvanced Cell Culture ModelsContent:≥ 2,000,000 cryopreserved cells per ampule
Promocell GmbH PromoCell HUF-c 500,000 Human Uterine Fibroblasts, cryopreserved
Primary Human Uterine Fibroblasts (HUF) are isolated from the uterine wall. During pregnancy, the uterine wall undergoes deep but reversible structural and biochemical changes. The uterine wall is the target of hormones and growth factors that act simultaneously and lead to extensive modifications of the extracellular matrix. This and other morphological and biochemical effects can be studied in vitro using HUF. Available formats:* Cryopreserved: Cryogenic vial containing 500.000 viable cells.
ATCC Primary Small Airway Epithelial; Cells, Fibrosis;Human (Homo sapiens)
Primary small airway epithelial cells were isolated from the respiratory tract of a donor with fibrosis. The cells have an application in microbial (eg, viral, bacterial) infection and pathogenesis, airway inflammation and wound healing, asthma, pulmonary fibrosis, chronic obstructive pulmonary disease, chronic bronchitis, toxicology, and testing of pharmaceuticals.
ATCC Saccharomyces cerevisiae; YVH10
An ampoule containing viable cells (yeast cells, spores, or agar cubes with mycelia) suspended in cryoprotectant
ATCC Pseudomonas; aeruginosa
This product is an ATCC manufactured and accessioned progeny of 39327 cited in US Patent Number 4,659,670.
ATCC Aeromonas hydrophila
Aeromonas hydrophila strain [CDC 359-60, IAM 12460, NCIB 9240, NCMB 86, NCTC 8049, RH 250] was isolated from a tin of milk with a fishy odor. This bacterial type strain is whole-genome sequenced and can be used in water testing.
ATCC Human parainfluenza; virus 4b; Strain: CH 19503
Human parainfluenza virus 4b strain CH 19503 was isolated from a child with a respiratory tract infection in Washington, DC, and was deposited by the Centers for Disease Control and Prevention. This animal virus can be propagated in NCI-H292 [H292] cells (ATCC CRL-1848) and has applications in infectious disease and respiratory disease research.
Eurofins Discoverx ChemiScreen V2 Vasopressin Receptor Stable Cell Line, 2 vials. (HTS060C)
The ChemiScreen V2 Vasopressin Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. vasopressin) based activation of AVPR2 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses AVPR2 alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of AVPR2, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
ATCC Staphylococcus aureus; subsp. aureus
Staphylococcus aureus subsp. aureus strain UT 25 is a clinical specimen isolated in 2003 from tracheal aspirate. This strain is the negative control for the inducible clindamycin-resistant “D” test.
Sciencell Research Laboratories Human Brain Vascular Pericytes, 5 x 10^5 cells/vial, (Cells Only)
Isolated from human brain. HBVP are cryopreserved at passage one after purification and delivered frozen. Each vial contains >5 x 10^5 cells in 1 ml volume.
ATCC Quantitative Genomic DNA from; Lactiplantibacillus plantarum; Strain: 17-5
Quantitative genomic DNA from Lactiplantibacillus plantarum strain 17-5 can be used for assay development, verification, and validation as well as monitoring of day-to-day test variation and lot-to-lot performance of molecular-based assays. The quantitative format allows for the generation of a standard curve for quantitative PCR (qPCR) to determine bacterial load.